Setting the initial tolerance when you know little about optimal parameter values

Use an initial tolerance of 10 in the Optimization Properties dialog box when you know very little about the optimal parameter values; otherwise, the algorithm will take a very long time to search a short distance in parameter space.

Once optimal values are found, the parameterUnknowns can be reinitialized with the new optimal values and the optimization can be rerun with a lower tolerance.

Though the algorithm tries to avoid local minima, to verify that the values found are optimal, run the optimizer with different initial values supplied to the parameterUnknowns.